The nickname "Gateway to the West" was given to St. Louis because of the importance the city had in expanding the United States westward. Millions of people had to come to St. Louis before they traveled westward. The city was where they pick up much needed supplies before they continued west. Many of them stayed, such as Daniel Boone and his family who settled in St. Charles County near Defiance. But many of the Kentuckians he brought with them continued westward, or northward. The cities of Hannibal, Clarksville and Louisiana Missouri were settled by so many men and women from Kentucky and Tennessee that the area was given the name "Little Dixie". The Boone family established the Boone's Lick Trail from St. Charles that went to salt deposits they discovered in Franklin in Howard County. The Boone's Lick Trail was the main route to connect to the Sante Fe Trail, the Oregon Trail or the California Trail which all went further west. The El Camino Real or "Royal Road" was another major land route from St. Louis that allowed settlers to move south to the cities of Kimmswick, Sainte Genevieve, Cape Girardeau and ultimately New Madrid Missouri.